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How does Epstein–Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?
A defining characteristic of the aggressive B cell tumour Burkitt's lymphoma (BL) is a reciprocal chromosomal translocation that activates the Myc oncogene by juxtaposing it to one of the immunoglobulin gene loci. The consequences of activating Myc include cell growth and proliferation that can...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academic Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770905/ https://www.ncbi.nlm.nih.gov/pubmed/19635566 http://dx.doi.org/10.1016/j.semcancer.2009.07.007 |