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Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease without clearly known disease causes. Recent epidemiological and animal studies suggest that the supplementation of dietary antioxidants (e.g., vitamins C and E) decreases cancer risk, implying that increased reactive oxygen species (R...

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Detalles Bibliográficos
Autores principales: Kong, Bo, Qia, Chengjia, Erkan, Mert, Kleeff, Jörg, Michalski, Christoph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771311/
https://www.ncbi.nlm.nih.gov/pubmed/24062691
http://dx.doi.org/10.3389/fphys.2013.00246