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Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease without clearly known disease causes. Recent epidemiological and animal studies suggest that the supplementation of dietary antioxidants (e.g., vitamins C and E) decreases cancer risk, implying that increased reactive oxygen species (R...

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Detalles Bibliográficos
Autores principales:	Kong, Bo, Qia, Chengjia, Erkan, Mert, Kleeff, Jörg, Michalski, Christoph W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771311/ https://www.ncbi.nlm.nih.gov/pubmed/24062691 http://dx.doi.org/10.3389/fphys.2013.00246

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