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Protecting a transgene expression from the HAC-based vector by different chromatin insulators

Human artificial chromosomes (HACs) are vectors that offer advantages of capacity and stability for gene delivery and expression. Several studies have even demonstrated their use for gene complementation in gene-deficient recipient cell lines and animal transgenesis. Recently, we constructed an adva...

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Detalles Bibliográficos
Autores principales: Lee, Nicholas CO, Kononenko, Artem V., Lee, Hee-Sheung, Tolkunova, Elena N., Liskovykh, Mikhail A., Masumoto, Hiroshi, Earnshaw, William C., Tomilin, Alexey N., Larionov, Vladimir, Kouprina, Natalay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771377/
https://www.ncbi.nlm.nih.gov/pubmed/23677492
http://dx.doi.org/10.1007/s00018-013-1362-9