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Protecting a transgene expression from the HAC-based vector by different chromatin insulators
Human artificial chromosomes (HACs) are vectors that offer advantages of capacity and stability for gene delivery and expression. Several studies have even demonstrated their use for gene complementation in gene-deficient recipient cell lines and animal transgenesis. Recently, we constructed an adva...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Basel
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771377/ https://www.ncbi.nlm.nih.gov/pubmed/23677492 http://dx.doi.org/10.1007/s00018-013-1362-9 |