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pH-sensitive degradable nanoparticles for highly efficient intracellular delivery of exogenous protein

BACKGROUND: Encapsulating exogenous proteins into a nanosized particulate system for delivery into cells is a great challenge. To address this issue, we developed a novel nanoparticle delivery method that differs from the nanoparticles reported to date because its core was composed of cross-linked d...

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Détails bibliographiques
Auteurs principaux: Xu, Dan, Wu, Fei, Chen, Yinghui, Wei, Liangming, Yuan, Weien
Format: Online Article Texte
Langue:English
Publié: Dove Medical Press 2013
Sujets:
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771747/
https://www.ncbi.nlm.nih.gov/pubmed/24039423
http://dx.doi.org/10.2147/IJN.S47701