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3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer

It should be noted that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is a protein encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by several growth factors and hormones. PDK1 is a crucial kinase that functions downstream of phosphoinositide 3-kinase acti...

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Detalles Bibliográficos
Autores principales: Fyffe, Chanse, Falasca, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771848/
https://www.ncbi.nlm.nih.gov/pubmed/24039447
http://dx.doi.org/10.2147/CMAR.S35026