A Glycosphingolipid Binding Domain Controls Trafficking and Activity of the Mammalian Notch Ligand Delta-Like 1

The activity of Notch ligands is tightly regulated by trafficking events occurring both before and after ligand-receptor interaction. In particular endocytosis and recycling have been shown to be required for full signaling activity of the ligands before they encounter the Notch receptor. However li...

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Detalles Bibliográficos
Autores principales: Heuss, Sara Farrah, Tarantino, Nadine, Fantini, Jacques, Ndiaye-Lobry, Delphine, Moretti, Julien, Israël, Alain, Logeat, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771905/
https://www.ncbi.nlm.nih.gov/pubmed/24069306
http://dx.doi.org/10.1371/journal.pone.0074392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771905/
https://www.ncbi.nlm.nih.gov/pubmed/24069306
http://dx.doi.org/10.1371/journal.pone.0074392

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