Cargando…

The Small Molecule Wnt Signaling Modulator ICG-001 Improves Contractile Function in Chronically Infarcted Rat Myocardium

The adult mammalian heart has limited capability for self-repair after myocardial infarction. Therefore, therapeutic strategies that improve post-infarct cardiac function are critically needed. The small molecule ICG-001 modulates Wnt signaling and increased the expression of genes beneficial for ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasaki, Tomoyo, Hwang, Hyosook, Nguyen, Cu, Kloner, Robert A., Kahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771968/
https://www.ncbi.nlm.nih.gov/pubmed/24069374
http://dx.doi.org/10.1371/journal.pone.0075010