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The Small Molecule Wnt Signaling Modulator ICG-001 Improves Contractile Function in Chronically Infarcted Rat Myocardium
The adult mammalian heart has limited capability for self-repair after myocardial infarction. Therefore, therapeutic strategies that improve post-infarct cardiac function are critically needed. The small molecule ICG-001 modulates Wnt signaling and increased the expression of genes beneficial for ca...
Autores principales: | Sasaki, Tomoyo, Hwang, Hyosook, Nguyen, Cu, Kloner, Robert A., Kahn, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771968/ https://www.ncbi.nlm.nih.gov/pubmed/24069374 http://dx.doi.org/10.1371/journal.pone.0075010 |
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