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Breast Cancer Cells Induce Osteolytic Bone Lesions In vivo through a Reduction in Osteoblast Activity in Mice

Bone metastases are severely debilitating and have a significant impact on the quality of life of women with metastatic breast cancer. Treatment options are limited and in order to develop more targeted therapies, improved understanding of the complex mechanisms that lead to bone lesion development...

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Detalles Bibliográficos
Autores principales: Gregory, Laura S., Choi, Wilson, Burke, Leslie, Clements, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772030/
https://www.ncbi.nlm.nih.gov/pubmed/24069136
http://dx.doi.org/10.1371/journal.pone.0068103