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Mechanistic Model of Natural Killer Cell Proliferative Response to IL-15 Receptor Stimulation

Natural killer (NK) cells are innate lymphocytes that provide early host defense against intracellular pathogens, such as viruses. Although NK cell development, homeostasis, and proliferation are regulated by IL-15, the influence of IL-15 receptor (IL-15R)-mediated signaling at the cellular level ha...

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Detalles Bibliográficos
Autores principales: Zhao, Yun M., French, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772054/
https://www.ncbi.nlm.nih.gov/pubmed/24068905
http://dx.doi.org/10.1371/journal.pcbi.1003222