Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

A recent trend in drug development is to identify drug combinations or multi-target agents that effectively modify multiple nodes of disease-associated networks. Such polypharmacological effects may reduce the risk of emerging drug resistance by means of attacking the disease networks through synerg...

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Detalles Bibliográficos
Autores principales: Tang, Jing, Karhinen, Leena, Xu, Tao, Szwajda, Agnieszka, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772058/
https://www.ncbi.nlm.nih.gov/pubmed/24068907
http://dx.doi.org/10.1371/journal.pcbi.1003226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772058/
https://www.ncbi.nlm.nih.gov/pubmed/24068907
http://dx.doi.org/10.1371/journal.pcbi.1003226

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