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Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf

The Unfolded Protein Response (UPR) maintains homeostasis in the endoplasmic reticulum (ER) and defends against ER stress, an underlying factor in various human diseases. During the UPR, numerous genes are activated that sustain and protect the ER. These responses are known to involve the canonical...

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Detalles Bibliográficos
Autores principales: Glover-Cutter, Kira M., Lin, Stephanie, Blackwell, T. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772064/
https://www.ncbi.nlm.nih.gov/pubmed/24068940
http://dx.doi.org/10.1371/journal.pgen.1003701