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Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model

Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate quantitative model of ChR2 is necessary for in silico prediction of the resp...

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Detalles Bibliográficos
Autores principales: Williams, John C., Xu, Jianjin, Lu, Zhongju, Klimas, Aleksandra, Chen, Xuxin, Ambrosi, Christina M., Cohen, Ira S., Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772068/
https://www.ncbi.nlm.nih.gov/pubmed/24068903
http://dx.doi.org/10.1371/journal.pcbi.1003220