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Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model
Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate quantitative model of ChR2 is necessary for in silico prediction of the resp...
Autores principales: | Williams, John C., Xu, Jianjin, Lu, Zhongju, Klimas, Aleksandra, Chen, Xuxin, Ambrosi, Christina M., Cohen, Ira S., Entcheva, Emilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772068/ https://www.ncbi.nlm.nih.gov/pubmed/24068903 http://dx.doi.org/10.1371/journal.pcbi.1003220 |
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