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Negatively charged residues in the endodomain are critical for specific assembly of spike protein into murine coronavirus
Coronavirus spike (S) protein assembles into virions via its carboxy-terminus, which is composed of a transmembrane domain and an endodomain. Here, the carboxy-terminal charge-rich motif in the endodomain was verified to be critical for the specificity of S assembly into mouse hepatitis virus (MHV)....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published by Elsevier Inc.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772176/ https://www.ncbi.nlm.nih.gov/pubmed/23628137 http://dx.doi.org/10.1016/j.virol.2013.04.001 |