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Facile mutant identification via a single parental backcross method and application of whole genome sequencing based mapping pipelines

Forward genetic screens have identified numerous genes involved in development and metabolism, and remain a cornerstone of biological research. However, to locate a causal mutation, the practice of crossing to a polymorphic background to generate a mapping population can be problematic if the mutant...

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Detalles Bibliográficos
Autores principales: Allen, Robert S., Nakasugi, Kenlee, Doran, Rachel L., Millar, Anthony A., Waterhouse, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772335/
https://www.ncbi.nlm.nih.gov/pubmed/24062760
http://dx.doi.org/10.3389/fpls.2013.00362