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Quantitative full time course analysis of nonlinear enzyme cycling kinetics
Enzyme inhibition due to the reversible binding of reaction products is common and underlies the origins of negative feedback inhibition in many metabolic and signaling pathways. Product inhibition generates non-linearity in steady-state time courses of enzyme activity, which limits the utility of w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772379/ https://www.ncbi.nlm.nih.gov/pubmed/24029878 http://dx.doi.org/10.1038/srep02658 |