Modelling of human Wiskott–Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging

Wiskott–Aldrich syndrome (WAS) and X-linked neutropenia (XLN) are immunodeficiencies in which the function of several haematopoietic cell lineages is perturbed as a result of mutations in the actin regulator WASp. From in vitro cell biology experiments, and biochemical and structural approaches, we...

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Detalles Bibliográficos
Autores principales: Jones, Rebecca A., Feng, Yi, Worth, Austen J., Thrasher, Adrian J., Burns, Siobhan O., Martin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772384/
https://www.ncbi.nlm.nih.gov/pubmed/23868979
http://dx.doi.org/10.1242/jcs.128728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772384/
https://www.ncbi.nlm.nih.gov/pubmed/23868979
http://dx.doi.org/10.1242/jcs.128728

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