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3-(2,5-Di­methyl­phen­yl)-8-meth­oxy-2-oxo-1-aza­spiro­[4.5]dec-3-en-4-yl 3-(2-bromo-4-fluoro­phen­yl)acrylate

In the title compound, C(27)H(27)BrFNO(4), which is an inhibitor of acetyl-CoA carboxyl­ase, the cyclo­hexane ring displays a chair comformation with the spiro-C and meth­oxy-bearing C atoms deviating by 0.681 (7) and −0.655 (1) Å, resppectively, from the mean plane formed by the other four C atoms...

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Detalles Bibliográficos
Autores principales: Xu, Bing-Rong, He, Xing-Rui, Cheng, Jing-Li, Zhao, Jin-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772492/
https://www.ncbi.nlm.nih.gov/pubmed/24046635
http://dx.doi.org/10.1107/S160053681301430X