Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase

The ubiquitin-signaling pathway utilizes E1 activating, E2 conjugating, and E3 ligase enzymes to sequentially transfer the small modifier protein ubiquitin to a substrate protein. During the last step of this cascade different types of E3 ligases either act as scaffolds to recruit an E2 enzyme and s...

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Detalles Bibliográficos
Autores principales: Spratt, Donald E., Mercier, Pascal, Shaw, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772753/
https://www.ncbi.nlm.nih.gov/pubmed/24058416
http://dx.doi.org/10.1371/journal.pone.0074047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772753/
https://www.ncbi.nlm.nih.gov/pubmed/24058416
http://dx.doi.org/10.1371/journal.pone.0074047

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