Cargando…
Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase
The ubiquitin-signaling pathway utilizes E1 activating, E2 conjugating, and E3 ligase enzymes to sequentially transfer the small modifier protein ubiquitin to a substrate protein. During the last step of this cascade different types of E3 ligases either act as scaffolds to recruit an E2 enzyme and s...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772753/ https://www.ncbi.nlm.nih.gov/pubmed/24058416 http://dx.doi.org/10.1371/journal.pone.0074047 |