Cargando…

Reactivation of Estrogen Receptor α by Vorinostat Sensitizes Mesenchymal-Like Triple-Negative Breast Cancer to Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor

OBJECTIVE: Aminoflavone (AF) acts as a ligand of the aryl hydrocarbon receptor (AhR). Expression of estrogen receptor α (ERα) and AhR-mediated transcriptional induction of CYP1A1 can sensitize breast cancer cells to AF. The objective of this study was to investigate the combined antitumor effect of...

Descripción completa

Detalles Bibliográficos
Autores principales: Stark, Karri, Burger, Angelika, Wu, Jianmei, Shelton, Phillip, Polin, Lisa, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772827/
https://www.ncbi.nlm.nih.gov/pubmed/24058584
http://dx.doi.org/10.1371/journal.pone.0074525