Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn’s Disease?

The epoxygenase CYP2J2 has an emerging role in inflammation and vascular biology. The role of CYP2J2 in phagocytosis is not known and its regulation in human inflammatory diseases is poorly understood. Here we investigated the role of CYP2J2 in bacterial phagocytosis and its expression in monocytes...

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Detalles Bibliográficos
Autores principales: Bystrom, Jonas, Thomson, Scott J., Johansson, Jörgen, Edin, Matthew L., Zeldin, Darryl C., Gilroy, Derek W., Smith, Andrew M., Bishop-Bailey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772848/
https://www.ncbi.nlm.nih.gov/pubmed/24058654
http://dx.doi.org/10.1371/journal.pone.0075107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772848/
https://www.ncbi.nlm.nih.gov/pubmed/24058654
http://dx.doi.org/10.1371/journal.pone.0075107

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