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An Intragenic SRF-Dependent Regulatory Motif Directs Cardiac-Specific microRNA-1-1/133a-2 Expression

Transcriptional regulation is essential for any gene expression including microRNA expression. MiR-1-1 and miR-133a-2 are essential microRNAs (miRs) involved in cardiac and skeletal muscle development and diseases. Early studies reveal two regulatory enhancers, an upstream and an intragenic, that di...

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Detalles Bibliográficos
Autores principales: Li, Qi, Guo, Junli, Lin, Xi, Yang, Xiangsheng, Ma, Yanlin, Fan, Guo-Chang, Chang, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772891/
https://www.ncbi.nlm.nih.gov/pubmed/24058688
http://dx.doi.org/10.1371/journal.pone.0075470