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A marriage of two “Methusalem” drugs for the treatment of psoriasis?: Arguments for a pilot trial with metformin as add-on for methotrexate

In this article we present arguments that the “antidiabetic” drug metformin could be useful as an add-on therapy to methotrexate for the treatment of psoriasis and, perhaps, for rheumatoid arthritis as well. Biochemical data suggest that both drugs may share a common cellular target, the AMP-activat...

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Detalles Bibliográficos
Autores principales: Glossmann, Hartmut, Reider, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772913/
https://www.ncbi.nlm.nih.gov/pubmed/24194965
http://dx.doi.org/10.4161/derm.23874