Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis

Pharmacological stabilization of hypoxia-inducible factor (HIF) through prolyl hydroxylase (PHD) inhibition limits mucosal damage associated with models of murine colitis. However, little is known about how PHD inhibitors (PHDi) influence systemic immune function during mucosal inflammation or the r...

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Detalles Bibliográficos
Autores principales: Keely, Simon, Campbell, Eric L., Baird, Alan W., Hansbro, Philip M., Shalwitz, Robert A., Kotsakis, Anna, McNamee, Eoin N., Eltzschig, Holger K., Kominsky, Douglas J., Colgan, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772994/
https://www.ncbi.nlm.nih.gov/pubmed/23695513
http://dx.doi.org/10.1038/mi.2013.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772994/
https://www.ncbi.nlm.nih.gov/pubmed/23695513
http://dx.doi.org/10.1038/mi.2013.29

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