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(#Issue1)Medium optimization of Streptomyces sp. 17944 for tirandamycin B production and isolation and structural elucidation of tirandamycins H, I, and J()

We have recently isolated tirandamycin (TAM) B from Streptomyces sp. 17944 as a Brugia malayi AsnRS (BmAsnRS) inhibitor that efficiently kills the adult B. malayi parasites and does not exhibit general cytotoxicity to human hepatic cells. We now report (i) the comparison of metabolite profiles of S....

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Detalles Bibliográficos
Autores principales: Rateb, Mostafa E., Yu, Zhiguo, Yan, Yijun, Yang, Dong, Huang, Tingting, Vodanovic-Jankovic, Sanja, Kron, Michael A., Shen, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773001/
https://www.ncbi.nlm.nih.gov/pubmed/23715040
http://dx.doi.org/10.1038/ja.2013.50