In Vivo Evidence of Increased nNOS Activity in Acute MPTP Neurotoxicity: A Functional Pharmacological MRI Study

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin commonly used to produce an animal model of Parkinson's disease. Previous studies have suggested a critical role for neuronal nitric oxide (NO) synthase- (nNOS-) derived NO in the pathogenesis of MPTP. However, NO activity is d...

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Detalles Bibliográficos
Autores principales: Siow, Tiing Yee, Chen, Chiao-Chi V., Wan, Nina, Chow, Kai-Ping N., Chang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773403/
https://www.ncbi.nlm.nih.gov/pubmed/24069609
http://dx.doi.org/10.1155/2013/964034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773403/
https://www.ncbi.nlm.nih.gov/pubmed/24069609
http://dx.doi.org/10.1155/2013/964034

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