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NOD2, an Intracellular Innate Immune Sensor Involved in Host Defense and Crohn's Disease
Nucleotide binding oligomerization domain 2 (NOD2) is an intracellular sensor for small peptides derived from the bacterial cell wall component, peptidoglycan. Recent studies have uncovered unexpected functions of NOD2 in innate immune responses such as induction of type I IFN and facilitation of au...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773501/ https://www.ncbi.nlm.nih.gov/pubmed/21750585 http://dx.doi.org/10.1038/mi.2011.29 |