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Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1β, and Tumor Necrosis Factor-α via a NF-κB-Dependent Mechanism in HaCaT Keratinocytes

To investigate whether palmitic acid can be responsible for the induction of inflammatory processes, HaCaT keratinocytes were treated with palmitic acid at pathophysiologically relevant concentrations. Secretion levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β),...

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Detalles Bibliográficos
Autores principales: Zhou, Bing-rong, Zhang, Jia-an, Zhang, Qian, Permatasari, Felicia, Xu, Yang, Wu, Di, Yin, Zhi-qiang, Luo, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774064/
https://www.ncbi.nlm.nih.gov/pubmed/24078775
http://dx.doi.org/10.1155/2013/530429