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Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

Wzx flippases are crucial for bacterial cell surface polysaccharide assembly as they transport undecaprenyl pyrophosphate-linked sugar repeat units from the cytoplasmic to the periplasmic leaflets of the inner membrane (IM) for final assembly. Our recently reported three-dimensional (3D) model struc...

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Detalles Bibliográficos
Autores principales: Islam, Salim T., Eckford, Paul D. W., Jones, Michelle L., Nugent, Timothy, Bear, Christine E., Vogel, Christian, Lam, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774195/
https://www.ncbi.nlm.nih.gov/pubmed/24023388
http://dx.doi.org/10.1128/mBio.00678-13