Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response

Glucocorticoids (GCs) are steroid hormones widely used as pharmaceutical interventions, which act mainly by regulating gene expression levels. A large fraction of patients (~30%), especially those of African descent, show a weak response to treatment. To interrogate the contribution of variable tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Maranville, Joseph C., Baxter, Shaneen S., Torres, Jason M., Di Rienzo, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774530/
https://www.ncbi.nlm.nih.gov/pubmed/22158329
http://dx.doi.org/10.1038/tpj.2011.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774530/
https://www.ncbi.nlm.nih.gov/pubmed/22158329
http://dx.doi.org/10.1038/tpj.2011.55

Ejemplares similares