Acquisition of RGC phenotype in human Müller glia with stem cell characteristics is accompanied by upregulation of functional nicotinic acetylcholine receptors

PURPOSE: Human Müller glia with stem cell characteristics (hMGSCs) can be induced to express genes and proteins of retinal ganglion cells (RGCs) upon in vitro inhibition of Notch-1 activity. However, it is not known whether expression of these markers is accompanied by acquisition of RGC function. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Becker, Silke, Singhal, Shweta, Jones, Megan F., Eastlake, Karen, Cottrill, Phillippa B., Jayaram, Hari, Limb, G. Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774575/
https://www.ncbi.nlm.nih.gov/pubmed/24049438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774575/
https://www.ncbi.nlm.nih.gov/pubmed/24049438

Ejemplares similares