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Inflammatory Mediators Influence the Expression of Nociceptin and Its Receptor in Human Whole Blood Cultures

BACKGROUND: Nociceptin/orphanin FQ and its receptor (NOP) are involved in immune responses, inflammation and pain processing. The aim of this study was to investigate the modulation of NOP and prepro-nociceptin (PNoc), the precursor of nociceptin, by inflammatory mediators in human whole blood. METH...

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Detalles Bibliográficos
Autores principales: Zhang, Lan, Stuber, Frank, Stamer, Ulrike M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774641/
https://www.ncbi.nlm.nih.gov/pubmed/24066107
http://dx.doi.org/10.1371/journal.pone.0074138