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Inflammatory Mediators Influence the Expression of Nociceptin and Its Receptor in Human Whole Blood Cultures
BACKGROUND: Nociceptin/orphanin FQ and its receptor (NOP) are involved in immune responses, inflammation and pain processing. The aim of this study was to investigate the modulation of NOP and prepro-nociceptin (PNoc), the precursor of nociceptin, by inflammatory mediators in human whole blood. METH...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774641/ https://www.ncbi.nlm.nih.gov/pubmed/24066107 http://dx.doi.org/10.1371/journal.pone.0074138 |