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Systematic Analyses of the Cytotoxic Effects of Compound 11a, a Putative Synthetic Agonist of Photoreceptor-Specific Nuclear Receptor (PNR), in Cancer Cell Lines

Photoreceptor cell-specific receptor (PNR/NR2E3) is an orphan nuclear receptor that plays a critical role in retinal development and photoreceptor maintenance. The disease-causing mutations in PNR have a pleiotropic effect resulting in varying retinal diseases. Recently, PNR has been implicated in c...

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Detalles Bibliográficos
Autores principales: Zhao, Zibo, Wang, Lu, Wen, Zhi, Ayaz-guner, Serife, Wang, Yidan, Ahlquist, Paul, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774666/
https://www.ncbi.nlm.nih.gov/pubmed/24066170
http://dx.doi.org/10.1371/journal.pone.0075198