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Virtual Screening Models for Prediction of HIV-1 RT Associated RNase H Inhibition

The increasing resistance to current therapeutic agents for HIV drug regiment remains a major problem for effective acquired immune deficiency syndrome (AIDS) therapy. Many potential inhibitors have today been developed which inhibits key cellular pathways in the HIV cycle. Inhibition of HIV-1 rever...

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Detalles Bibliográficos
Autores principales: Poongavanam, Vasanthanathan, Kongsted, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774690/
https://www.ncbi.nlm.nih.gov/pubmed/24066050
http://dx.doi.org/10.1371/journal.pone.0073478