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Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?
FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain. Irisin was proposed to be secreted by skeletal muscle cells in...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774709/ https://www.ncbi.nlm.nih.gov/pubmed/24052909 http://dx.doi.org/10.4161/adip.26082 |