Inactivated Orf Virus Shows Antifibrotic Activity and Inhibits Human Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Replication in Preclinical Models

Inactivated orf virus (iORFV), strain D1701, is a potent immune modulator in various animal species. We recently demonstrated that iORFV induces strong antiviral activity in animal models of acute and chronic viral infections. In addition, we found D1701-mediated antifibrotic effects in different ra...

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Detalles Bibliográficos
Autores principales: Paulsen, Daniela, Urban, Andreas, Knorr, Andreas, Hirth-Dietrich, Claudia, Siegling, Angela, Volk, Hans-Dieter, Mercer, Andrew A., Limmer, Andreas, Schumak, Beatrix, Knolle, Percy, Ruebsamen-Schaeff, Helga, Weber, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774719/
https://www.ncbi.nlm.nih.gov/pubmed/24066148
http://dx.doi.org/10.1371/journal.pone.0074605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774719/
https://www.ncbi.nlm.nih.gov/pubmed/24066148
http://dx.doi.org/10.1371/journal.pone.0074605

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