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A Slow Axon Antidromic Blockade Hypothesis for Tremor Reduction via Deep Brain Stimulation

Parkinsonian and essential tremor can often be effectively treated by deep brain stimulation. We propose a novel explanation for the mechanism by which this technique ameliorates tremor: a reduction of the delay in the relevant motor control loops via preferential antidromic blockade of slow axons....

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Detalles Bibliográficos
Autores principales: García, Míriam R., Pearlmutter, Barak A., Wellstead, Peter E., Middleton, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774723/
https://www.ncbi.nlm.nih.gov/pubmed/24066049
http://dx.doi.org/10.1371/journal.pone.0073456