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A Slow Axon Antidromic Blockade Hypothesis for Tremor Reduction via Deep Brain Stimulation
Parkinsonian and essential tremor can often be effectively treated by deep brain stimulation. We propose a novel explanation for the mechanism by which this technique ameliorates tremor: a reduction of the delay in the relevant motor control loops via preferential antidromic blockade of slow axons....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774723/ https://www.ncbi.nlm.nih.gov/pubmed/24066049 http://dx.doi.org/10.1371/journal.pone.0073456 |