Unique Anti-Glioblastoma Activities of Hypericin Are at the Crossroad of Biochemical and Epigenetic Events and Culminate in Tumor Cell Differentiation

Failure of conventional therapies to alleviate glioblastoma (GBM) fosters search for novel therapeutic strategies. These include epigenetic modulators as histone deacetylase inhibitors (HDACi), which relax abnormally compact tumor cell chromatin organization, enabling cells to overcome blockage in d...

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Detalles Bibliográficos
Autores principales: Dror, Naama, Mandel, Mathilda, Lavie, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774735/
https://www.ncbi.nlm.nih.gov/pubmed/24066060
http://dx.doi.org/10.1371/journal.pone.0073625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774735/
https://www.ncbi.nlm.nih.gov/pubmed/24066060
http://dx.doi.org/10.1371/journal.pone.0073625

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