CD4(+) T Cells Play a Critical Role in the Generation of Primary and Memory Antitumor Immune Responses Elicited by SA-4-1BBL and TAA-Based Vaccines in Mouse Tumor Models

The role of CD4(+) T cells in the generation of therapeutic primary and memory immune responses in cancer diverse immunotherapy settings remains ambiguous. We herein investigated this issue using two vaccine formulations containing a novel costimulatory molecule, SA-4-1BBL, as adjuvant and HPV E7 or...

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Detalles Bibliográficos
Autores principales: Sharma, Rajesh K., Yolcu, Esma S., Srivastava, Abhishek K., Shirwan, Haval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774737/
https://www.ncbi.nlm.nih.gov/pubmed/24066030
http://dx.doi.org/10.1371/journal.pone.0073145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774737/
https://www.ncbi.nlm.nih.gov/pubmed/24066030
http://dx.doi.org/10.1371/journal.pone.0073145

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