Regulation of the F11, Klkb1, Cyp4v3 Gene Cluster in Livers of Metabolically Challenged Mice

Single nucleotide polymorphisms (SNPs) in a 4q35.2 locus that harbors the coagulation factor XI (F11), prekallikrein (KLKB1), and a cytochrome P450 family member (CYP4V2) genes are associated with deep venous thrombosis (DVT). These SNPs exert their effect on DVT by modifying the circulating levels...

Descripción completa

Detalles Bibliográficos
Autores principales: Safdar, Huma, Cleuren, Audrey C. A., Cheung, Ka Lei, Gonzalez, Frank J., Vos, Hans L., Inoue, Yusuke, Reitsma, Pieter H., van Vlijmen, Bart J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774739/
https://www.ncbi.nlm.nih.gov/pubmed/24066149
http://dx.doi.org/10.1371/journal.pone.0074637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774739/
https://www.ncbi.nlm.nih.gov/pubmed/24066149
http://dx.doi.org/10.1371/journal.pone.0074637

Ejemplares similares