Poliovirus 2A Protease Triggers a Selective Nucleo-Cytoplasmic Redistribution of Splicing Factors to Regulate Alternative Pre-mRNA Splicing

Poliovirus protease 2A (2A(pro)) obstructs host gene expression by reprogramming transcriptional and post-transcriptional regulatory events during infection. Here we demonstrate that expression of 2A(pro) induces a selective nucleo-cytoplasm translocation of several important RNA binding proteins an...

Descripción completa

Detalles Bibliográficos
Autores principales: Álvarez, Enrique, Castelló, Alfredo, Carrasco, Luis, Izquierdo, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774746/
https://www.ncbi.nlm.nih.gov/pubmed/24066065
http://dx.doi.org/10.1371/journal.pone.0073723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774746/
https://www.ncbi.nlm.nih.gov/pubmed/24066065
http://dx.doi.org/10.1371/journal.pone.0073723

Ejemplares similares