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Controlling Seizure-Like Events by Perturbing Ion Concentration Dynamics with Periodic Stimulation
We investigate the effects of adding periodic stimulation to a generic, conductance-based neuron model that includes ion concentration dynamics of sodium and potassium. Under conditions of high extracellular potassium, the model exhibits repeating, spontaneous, seizure-like bursting events associate...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774776/ https://www.ncbi.nlm.nih.gov/pubmed/24066075 http://dx.doi.org/10.1371/journal.pone.0073820 |