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Controlling Seizure-Like Events by Perturbing Ion Concentration Dynamics with Periodic Stimulation

We investigate the effects of adding periodic stimulation to a generic, conductance-based neuron model that includes ion concentration dynamics of sodium and potassium. Under conditions of high extracellular potassium, the model exhibits repeating, spontaneous, seizure-like bursting events associate...

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Detalles Bibliográficos
Autores principales:	Owen, Jeremy A., Barreto, Ernest, Cressman, John R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774776/ https://www.ncbi.nlm.nih.gov/pubmed/24066075 http://dx.doi.org/10.1371/journal.pone.0073820

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