Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

Human coronavirus OC43 (HCoV-OC43) is a causative agent of the common cold. The nucleocapsid (N) protein, which is a major structural protein of CoVs, binds to the viral RNA genome to form the virion core and results in the formation of the ribonucleoprotein (RNP) complex. We have solved the crystal...

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Detalles Bibliográficos
Autores principales: Chen, I.-Jung, Yuann, Jeu-Ming P., Chang, Yu-Ming, Lin, Shing-Yen, Zhao, Jincun, Perlman, Stanley, Shen, Yo-Yu, Huang, Tai-Huang, Hou, Ming-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774783/
https://www.ncbi.nlm.nih.gov/pubmed/23501675
http://dx.doi.org/10.1016/j.bbapap.2013.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774783/
https://www.ncbi.nlm.nih.gov/pubmed/23501675
http://dx.doi.org/10.1016/j.bbapap.2013.03.003

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