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Evolution of the R2 Retrotransposon Ribozyme and Its Self-Cleavage Site

R2 is a non-long terminal repeat retrotransposon that inserts site-specifically in the tandem 28S rRNA genes of many animals. Previously, R2 RNA from various species of Drosophila was shown to self-cleave from the 28S rRNA/R2 co-transcript by a hepatitis D virus (HDV)-like ribozyme encoded at its 5&...

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Detalles Bibliográficos
Autores principales: Eickbush, Danna G., Burke, William D., Eickbush, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774820/
https://www.ncbi.nlm.nih.gov/pubmed/24066021
http://dx.doi.org/10.1371/journal.pone.0066441