Mithramycin A induces apoptosis by regulating the mTOR/Mcl-1/tBid pathway in androgen-independent prostate cancer cells

Mithramycin A (Mith) is an aureolic acid-type polyketide produced by various soil bacteria of the genus Streptomyces. Mith inhibits myeloid cell leukemia-1 (Mcl-1) to induce apoptosis in prostate cancer, but the molecular mechanism underlying this process has not been fully elucidated. The aim of th...

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Detalles Bibliográficos
Autores principales: Choi, Eun-Sun, Chung, Taeho, Kim, Jun-Sung, Lee, Hakmo, Kwon, Ki Han, Cho, Nam-Pyo, Cho, Sung-Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774928/
https://www.ncbi.nlm.nih.gov/pubmed/24062605
http://dx.doi.org/10.3164/jcbn.13-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774928/
https://www.ncbi.nlm.nih.gov/pubmed/24062605
http://dx.doi.org/10.3164/jcbn.13-28

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